Fig. 8

Forest plot and pooled RR and 95 % CI for subgroup ORR: anti-angiogenesis therapy versus non-anti-angiogenesis therapy. RR risk ratios, CI confidence intervals, ORR overall response rate. (a: ORR of subgroups of angiogenesis inhibitors alone threapy; b: ORR of subgroups of angiogenesis inhibitors combined with chemotherapy threapy; c: ORR of subgroups of the first line threapy; d: ORR of subgroups of the second line threapy; e: ORR of subgroups of anti-VEGF threapy; f: ORR of subgroups of anti-VEGFR and multiple receptor inhibitors threapy)