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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: PD-L1 is upregulated by EBV-driven LMP1 through NF-κB pathway and correlates with poor prognosis in natural killer/T-cell lymphoma

Fig. 2

Expression of PD-L1 was upregulated by LMP1 in NK-92 cells. a, b Infection efficiency of LV5-LMP1 vector (a) and LV5 vector (LV5-NC, b) in NK-92 cell line at a multiplicity of infection (MOI) of 100, 200, and 300, respectively. The level of c LMP1 and PD-L1 proteins detected by western blot, d LMP1 and e PD-L1 mRNA detected by quantitative real-time PCR, f soluble PD-L1 protein in cell culture supernatant detected by ELISA, and g, h PD-L1 expression on cell surface detected by flow cytometry in LMP1-expressing NK92 (LMP1) and negative control NK92 (NC) cell lines, respectively. ** P < 0.05

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