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Fig. 3 | Journal of Hematology & Oncology

Fig. 3

From: Targeting of PI3K/AKT/mTOR pathway to inhibit T cell activation and prevent graft-versus-host disease development

Fig. 3

Effect of BKM120 and BEZ235 on Th1/Th2 cytokine secretion. Concentration of IL-2, IFN-γ, TNF-α, IL-4, IL-10, and IL-6 in the culture supernatant of isolated T cells stimulated in the presence of different concentrations of BKM120 or BEZ235. Concentration values corresponding to unstimulated untreated samples are also shown. Data represent the mean ± SEM of at least three independent experiments. #p < 0.05 with respect to stimulated untreated samples (0 μM)

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Journal of Hematology & Oncology

ISSN: 1756-8722

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