Fig. 4
From: T cells in multiple myeloma display features of exhaustion and senescence at the tumor site
Differential expression of T cell markers in BM of newly diagnosed and refractory myeloma patients. a Percentage of cell surface expression of exhaustion markers PD1, CTLA-4, CD160, 2B4 was quantified on CD8+ effector T cells from patients with newly diagnosed myeloma (MM naive) and treated myeloma (MM Tx) compared to healthy donors. b Similar, expression of senescent markers CD57 and CD28 was investigated by flow cytometry. (Healthy n = 7–12; myeloma newly diagnosed n = 7–11; treated myeloma n = 5–6; median with IQR is shown). Significance levels *p < 0.05; **p < 0.01; n.s. not significant