Fig. 7
RU cells stably transfected with MYC are biochemically and phenotypically similar with RR cells. a The protein levels of p-MYCS62, MYC, active β-catenin, β-catenin, pGSK3βS9, GSK3β, LEF1, and Sox2 in the stably transfected cell lines SupM2-RU-EV, SupM2-RU-MYC, and SupM2-RR-EV. b The relative mRNA levels of MYC, WNT2B, CTNNB1, and BCL9 in the three stable cell lines. c The diagram showed the design of mice xenograft study. d The tumor growth rates of the three stable cell lines in the mouse xenograft study. The right panel showed the representative tumors from the three groups at the termination point