Inflammasome components | Function | Location | Translocation | PMID | |
---|---|---|---|---|---|
ASC | ASC-b | Inflammasome adaptor | Cytoplasm | Nucleus | 20482797 |
ASC-c | Inflammasome adaptor | Cytoplasm | Nucleus | ||
ASC-d | Cytosol | Nucleus | |||
Pro-caspase-1 | Pro-caspase-1 and caspase prodomain promote translocation | Cytosol | Nucleus | 9726961 | |
NLRP3 | Nuclear DNA-binding transcription factor | Cytosol | Nucleus | 26098997 | |
NLRA | Control transcription, inflammasome formation and transcriptional activity | Nucleus | 26194278 | ||
NLRC5 | Control transcription, inflammasome formation and transcriptional activity | Nuclear | 26194278 |