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Table 2 Univariate analyses of factors associated with OS and TTR

From: Monoacylglycerol lipase promotes progression of hepatocellular carcinoma via NF-κB-mediated epithelial-mesenchymal transition

 

OS

TTR

Variablesa

HR (95% CI)

P

HR (95% CI)

P

Gender (male vs. female)

1.375 (0.751–2.518)

0.302

1.072 (0.605–1.898)

0.811

Age (≤50 vs. >50 years)

0.863 (0.577–1.289)

0.471

1.140 (0.748–1.738)

0.542

HBsAg (negative vs. positive)

1.444 (0.788–2.646)

0.234

1.833 (0.974–3.449)

0.061

HCV (negative vs. positive)

1.157 (0.365–3.669)

0.805

0.612 (0.150–2.503)

0.494

Liver cirrhosis (no vs. yes)

1.337 (0.865–2.067)

0.192

1.476 (0.947–2.299)

0.085

AFP (≤20 vs. >20 ng/ml)

1.408 (0.893–2.219)

0.140

1.005 (0.650–1.553)

0.983

Tumor number (single vs. multiple)

1.731 (1.160–2.581)

0.007

1.877 (1.247–2.826)

0.003

Tumor size (≤5 vs. >5 cm)

2.211 (1.461–3.345)

<0.001

1.936 (1.278–2.934)

0.002

Tumor encapsulation (complete vs. incomplete)

1.566 (1.049–2.338)

0.028

1.116 (0.744–1.676)

0.595

Microvascular invasion (absent vs. present)

1.602 (1.074–2.389)

0.021

1.556 (1.033–2.345)

0.035

Edmondson grade (I–II vs. III–IV)

1.401 (0.898–2.184)

0.137

1.282 (0.826–1.990)

0.268

TNM stage (I vs. II–III)

2.117 (1.026–4.369)

0.042

3.260 (1.423–7.468)

0.005

MAGL (low vs. high)

1.856 (1.220–2.823)

0.004

2.040 (1.331–3.128)

0.001

  1. OS overall survival, TTR time to recurrence, HR hazard ratio, CI confidence interval, HBsAg hepatitis B surface antigen, HCV hepatitis C virus, AFP alpha fetoprotein, TNM tumor node metastasis, MAGL monoacylglycerol lipase
  2. aVariables were analyzed by Cox proportional hazards regression model
  3. Italic numbers indicates that the variables might be associated with OS or TTR were subjected to the multivariate Cox analysis with 0.2 level for entry into the model