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Fig. 7 | Journal of Hematology & Oncology

Fig. 7

From: Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue

Fig. 7

Proposed mechanism of the oncogenic property of IL-6 in the prostate. The pro-inflammatory cytokine IL-6 in the prostate, as a result of inflammation or peri-prostatic obesity, induce autocrine and paracrine pathway and amplify inflammation in the prostate tissue environment and peri-prostate adipose tissue which subsequently induces transcriptional reprogramming in the prostate and tumorigenesis

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Journal of Hematology & Oncology

ISSN: 1756-8722

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