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Table 1 Summary of the prostate pathology of pbIl-6 mice and wild type littermate surveyed at various ages

From: Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue

Age (weeks)

16–20

24–28

52–72

>100

pbIL-6

 PIN

100%

100%

100%

100%

(13/13)

(11/11)

(16/16)

(10/10)

 Tumor (WD)

100%

100%

100%

100%

(13/13)

(11/11)

(16/16)

(10/10)

 Tumor (PD)

0/13

0/11

6.2%

20%

  

(1/16)

(2/10)

B6 (WT)

 PIN

0/20

4.5%

8.3%

12.5%

 

(1/22)

(1/12)

(1/8)

 Tumor (WD)

0/20

0/22

0/22

0/8

 Tumor (PD)

0/20

0/22

0/22

0/8

  1. PIN prostate intraepithelial neoplasia, WD well-differentiated tumor, PD poorly differentiated tumor