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Table 1 Summary of the prostate pathology of pbIl-6 mice and wild type littermate surveyed at various ages

From: Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue

Age (weeks) 16–20 24–28 52–72 >100
pbIL-6
 PIN 100% 100% 100% 100%
(13/13) (11/11) (16/16) (10/10)
 Tumor (WD) 100% 100% 100% 100%
(13/13) (11/11) (16/16) (10/10)
 Tumor (PD) 0/13 0/11 6.2% 20%
   (1/16) (2/10)
B6 (WT)
 PIN 0/20 4.5% 8.3% 12.5%
  (1/22) (1/12) (1/8)
 Tumor (WD) 0/20 0/22 0/22 0/8
 Tumor (PD) 0/20 0/22 0/22 0/8
  1. PIN prostate intraepithelial neoplasia, WD well-differentiated tumor, PD poorly differentiated tumor
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Journal of Hematology & Oncology

ISSN: 1756-8722

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