Fig. 8

miR-34a inhibits DMPM tumorigenicity. a STO, MesoII, and MP8 cells were transfected with miR-34a or Neg and, on day 0, implanted subcutaneously into the right flank of SCID mice. Micrographs show the mean tumor volumes ± SD measured at different time points after DMPM cell injection. (*p < 0.05, **p < 0.01 by two-tailed Student’s t test). b Cropped western blot for c-MET and AXL expression in frozen tumors derived from two additional mice sacrificed at different times (STO, 10 days; MesoII, 19 days; MP8, 25 days) after cell inoculum. Actin was used to confirm equal protein loading