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Table 1 Correlation between Klotho expression and clinical characteristics of DLBCL patients

From: Klotho, an anti-aging gene, acts as a tumor suppressor and inhibitor of IGF-1R signaling in diffuse large B cell lymphoma

Characteristics

No. of patients

Klotho expression

p value

Positive (%)

Negative

Age (years)

 <60

27

4(14.8%)

23

0.857

 ≥60

23

3(13.0%)

20

Gender

 Male

26

2(7.7%)

24

0.181

 Female

24

5(20.8%)

19

Ann Arbor stage

 I or II

12

5(41.7%)

7

0.002

 III or IV

38

2(5.3%)

36

B symptoms

 Present

14

2(14.3%)

12

0.971

 Absent

36

5(13.9%)

31

Subtype

 GCB

15

2(13.3%)

13

0.929

 Non-GCB

35

5(14.3%)

30

Serum LDH

 Normal

35

5(14.3%)

30

0.929

 Elevated

15

2(13.3%)

13

Extranodal involvement

 Absent

28

4(14.3%)

18

0.45

 Present

22

3(13.7%)

25

IPI score

 0–2

35

6(17.1%)

29

0.328

 3–5

15

1(6.7%)

14

  1. LDH lactate dehydrogenase, IPI international prognostic index