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Table 2 Multivariate analysis of adverse factors associated with survival outcomes and GVHD

From: Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

Outcome Hazard ratio (95% confidence interval) P value
Overall survival
 Previous RBC (>10) 6.8 (1.9–23.8) 0.003
 ECOG (>2) 2.9 (1.1–7.9) 0.032
Failure-free survival
 Previous RBC (>10) 5.4 (1.8–16.3) 0.003
 ECOG (>2) 3.0 (1.2–7.5) 0.022
II–IV aGVHD
 HID 1.3 (0.9–1.8) 0.181
III–IV aGVHD
 HID 1.6 (1.2–2.2) 0.006
  1. HID haploidentical donor, aGVHD acute graft-versus-host disease, cGVHD chronic graft-versus-host disease