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Table 2 Multivariate analysis of adverse factors associated with survival outcomes and GVHD

From: Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

Outcome

Hazard ratio (95% confidence interval)

P value

Overall survival

 Previous RBC (>10)

6.8 (1.9–23.8)

0.003

 ECOG (>2)

2.9 (1.1–7.9)

0.032

Failure-free survival

 Previous RBC (>10)

5.4 (1.8–16.3)

0.003

 ECOG (>2)

3.0 (1.2–7.5)

0.022

II–IV aGVHD

 HID

1.3 (0.9–1.8)

0.181

III–IV aGVHD

 HID

1.6 (1.2–2.2)

0.006

  1. HID haploidentical donor, aGVHD acute graft-versus-host disease, cGVHD chronic graft-versus-host disease