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Table 2 The advances of single-cell capture methods

From: Studying hematopoiesis using single-cell technologies

Methods Advantage Drawback Application
Mouth pipetting Low cost Time consuming Rare sample
Laser capture microdissection Visualization Time consuming Specific target
Flow cytometry Marker selection Require sorting MARS-seq
Microwell platform High throughput mRNA capture rate Cyto-seq
Microdroplet platform High throughput mRNA capture rate Drop-seq, inDrop
Fluidigm C1 platform Automatic library prep High cost qPCR, mRNA-seq
DEPArray Visualization High cost Specific target