Fig. 1

Downregulation of miR-194 in LSCC is correlated with T stages, lymph node metastasis, clinical stages, recurrence, and poor prognosis. a RT-qPCR analysis of the relative miR-194 expression in 44 pairs of LSCC tissues and adjacent normal tissues with Student’s t test. The relative miR-194 expression in two groups of LSCC tissues classified by age (b), T stage (c), lymph node metastasis (f) and clinical stage (g) were analyzed with Mann-Whitney U test. The relative miR-194 expression in three groups of LSCC tissues classified by differentiation (d) and primary location (e) were analyzed with Kruskal–Wallis test. h ROC curve analysis of the discrimination between LSCC tissues and adjacent normal tissues by miR-194. i Kaplan–Meier analysis of overall survival and disease-free survival curves for LSCC patients with high and low expression of miR-194. Data are presented as mean ± SD or median with the interquartile range. *P < 0.05; **P < 0.01; NS no statistical significance