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Fig. 9 | Journal of Hematology & Oncology

Fig. 9

From: Analyses of caspase-1-regulated transcriptomes in various tissues lead to identification of novel IL-1β-, IL-18- and sirtuin-1-independent pathways

Fig. 9

The meta-analysis of Sirt-1 microarray data identified 28 Sirt-1 globally regulated genes. a Heat map for fold changes of significantly changed genes with adj. p < 0.05 comparing Sirt1 KO to WT or comparing control to treatment or transgenic of Sirt-1. b The top five signatures of Sirt-1 globally regulated genes as revealed by Ingenuity Pathway Analysis (adj. p < 0.05)

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