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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: A novel monoclonal antibody against the von Willebrand Factor A2 domain reduces its cleavage by ADAMTS13

Fig. 1

Epitope mapping of SZ-179. a Schematic analysis of the human VWF. Domains are indicated. b VWFA1, VWFA2, GST-VWF73-H, and VWFA3 were separated by reduced 15% SDS-PAGE and detected with a mouse anti-His antibody (left) or SZ-179 (right). c Schematic analysis of 20 different VWFA2 mutants with His tags. d VWFA2 and its deletion mutants were separated by 15% reducing SDS-PAGE and detected by Western blotting with anti-His (top) or SZ-179 (bottom)

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