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Table 2 Dynamics of RUNX1-RUNX1T1 transcripts post-HSCT in patients in continuous CR

From: The dynamics of RUNX1-RUNX1T1 transcript levels after allogeneic hematopoietic stem cell transplantation predict relapse in patients with t(8;21) acute myeloid leukemia

Month post-HSCT

Number of patients evaluated

Median RUNX1-RUNX1T1 transcript levels (range)

Patients with ≥3-log reduction (%)

Patients with ≥4-log reduction (%)

P value*

1

174

0.011% (0–12.8%)

163 (93%)

121 (70%)

<0.0001

2

167

0.0062% (0–22.5%)

160 (96%)

132 (79%)

<0.0001

3

161

0 (0–17.8%)

153 (95%)

127 (79%)

<0.0001

4.5

126

0 (0–1.5%)

122 (97%)

93 (74%)

<0.0001

6

143

0 (0–2.4%)

139 (97%)

123 (86%)

0.001

9

113

0 (0–4.1%)

111 (98%)

99 (88%)

0.003

12

118

0 (0–0.66%)

116 (98%)

110 (93%)

0.10

18

90

0 (0–0.30%)

90 (100%)

87 (97%)

0.25

24

72

0 (0–0.30%)

72 (100%)

68 (94%)

0.12

30

23

0 (0–0.49%)

22 (96%)

22 (96%)

1.0

36

27

0 (0–0.005%)

27 (100%)

27 (100%)

1.0

  1. *Comparison of the frequency of patients with a ≥3-log reduction with the frequency of patients with a ≥4-log reduction at each time point