Table 1 Top 10 of differentially methylated miRNAs in prostate cancer
CHR | miRNA | Coordinates (GRCh37.p5) | RELATION CPG ISLAND | miRBase/MirgeneDB [34] | Gene family | Clustered miRNA | Methylation frequency (array) |
|---|---|---|---|---|---|---|---|
22 | MIR130B;MIR301B | chr22: 22007593-22007674 [+] | S_Shore | Ok/ok | MIR130 | MIR301B/130B | 0.76 |
17 | MIR152 | chr17: 46114527-46114613 [−] | Island | Ok/ok | MIR148 | 0.72 | |
2 | MIR1258 | chr2: 180725563-180725635 [−] | S_Shore | Ok/– | MIR1258 | 0.68 | |
16 | MIR762 | chr16: 30905224-30905306 [+] | N_Shore | Ok/– | MIR762 | 0.52 | |
11 | MIR34B;MIR34C | chr11: 111384164-111384240 [+] | Island | Ok/ok | MIR34 | MIR34B/34C | 0.44 |
15 | MIR9-3 | chr15: 89911248-89911337 [+] | N_Shore | Ok/ok | MIR9 | 0.44 | |
1 | MIR9-1 | chr1: 156390133-156390221 [−] | N_Shore | Ok/ok | MIR9 | 0.36 | |
11 | MIR129-2 | chr11: 43602944-43603033 [+] | Island | Ok/ok | 0.36 | ||
6 | MIR219-1 | chr6: 33175612-33175721 [+] | N_Shore | Ok/ok | MIR219 | 0.32 | |
11 | MIR210 | chr11: 568089-568198 [−] | Island | Ok/ok | MIR210 | 0.32 |