Fig. 6

Incidence of new or worsening grade 3 or 4 a anemia, b thrombocytopenia, and c leukopenia over time. Anemia, thrombocytopenia, and leukopenia were based on hematologic laboratory abnormalities. (asterisk) Placebo arm data are only shown up to 6 months because all patients randomized to placebo crossed over or discontinued within 3 months of the primary analysis