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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways

Fig. 2

YAP1 expression profile in colon cancer tissue microarray. A significantly increased staining of YAP1 was predominately found in the colon cancer samples. Strong staining (Q score ≥150) was found in stages IIIB, IIIC, IVA, and IVB suggesting that YAP1 expression may be associated with the progression of colon CA. Total number of samples (cancer 39 and normal tissues 9). a Representative micrographs of the tissue microarray are shown (stained with YAP1 antibody). b Quantitative analysis of YAP1 staining. The Q score of each sample was plotted and showed that strong YAP1 staining was associated in the tumor samples as compared to the normal tissues. ***P < 0.001. Scoring analysis was performed using Q score as established previously [49]

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