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Fig. 3 | Journal of Hematology & Oncology

Fig. 3

From: Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1

Fig. 3

The effects of metformin and ATO on the mTORC1 and AMPK/MAPK pathways in ICC in vitro. a and c The effect of metformin and ATO single or combination treatment on the active status of mTORC1, AMPK/MAPK, and ERK3 pathways of ICC cells was determined by western blotting. b and d The data were quantified and are represented as the means ± SD from three independent experiments. (Combination vs metformin * P < 0.05, combination vs ATO # P < 0.05)

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Journal of Hematology & Oncology

ISSN: 1756-8722

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