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Fig. 6 | Journal of Hematology & Oncology

Fig. 6

From: Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1

Fig. 6

Downregulation of ERK3 rescues ICC cell survival in cells treated with both metformin and ATO. a Downregulation of AMPK by specific siRNAs partially rescued ICC cell survival in cells treated with metformin and ATO (* P < 0.05). b The expression level of ERK3 was detected by western blot in ICC cells after MAPK6-specific siRNA interference

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