Skip to main content
Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: Next-generation sequencing and FISH studies reveal the appearance of gene mutations and chromosomal abnormalities in hematopoietic progenitors in chronic lymphocytic leukemia

Fig. 1

Cytogenetics and molecular characteristics of CD19+ and CD34+ cells. In the heatmap, rows correspond to the indicated alterations and each column represents individual CLL samples. Color-coded based on the gene and cytogenetic status (dark gray, altered; light gray, not-altered; white, not analyzed). For IGHV status: dark gray, unmutated; light gray, mutated. *Only mutations with VAF > 10% were considered for MACS isolated CD34+ cells considering the purities obtained. **Mutations in CD34+CD19− cells were assessed by ultra-deep NGS, considering mutations with VAF > 2%, taking into account the cell purities obtained from FACS sorting

Back to article page

Journal of Hematology & Oncology

ISSN: 1756-8722

Contact us