Fig. 1From: Activity of trabectedin and the PARP inhibitor rucaparib in soft-tissue sarcomasPARP activity measured during apoptosis. Percentage of PARP activity inhibition in IB111, IB115, IB136, and 93T449 after 48 h of treatment with 0.001, 0.00015, 0.007, or 0.00005 μM of trabectedin, respectively; 10, 1.3, 13, or 1 μM of rucaparib, respectively; or both drugs in combinationBack to article page