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Fig. 8 | Journal of Hematology & Oncology

Fig. 8

From: An imprinted non-coding genomic cluster at 14q32 defines clinically relevant molecular subtypes in osteosarcoma across multiple independent datasets

Fig. 8

Hierarchical clustering of aggressive and non-aggressive cell lines. Separation by hierarchical clustering of aggressive and non-aggressive cell lines based on 27 miRNAs from 14q32 that are significantly associated with recurrence in the clinical Boston cohort (clusters were the same whether the top 5 or all 27 miRNAs were used). Aggressive cell lines tend to segregate preferentially together. (Mann-Whitney p = 0.02 for supervised median expression difference between the two groups). Red: relative overexpression. Green: relative underexpression

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