Fig. 2From: Recent advances of highly selective CDK4/6 inhibitors in breast cancerChemical structures of CDK4/6 inhibitors. The chemical structures of the pan-CDK inhibitor (a) flavopiridol and the highly selective inhibitors including (b) palbociclib (PD0332991), (c) ribociclib (LEE011) and (d) abemaciclib (LY2835219) are shown. The reported half-maximal inhibitory concentration (IC50) values of these inhibitors are shownBack to article page