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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: The chimeric monoclonal antibody MHCSZ-123 against human von Willebrand factor A3 domain inhibits high-shear arterial thrombosis in a Rhesus monkey model

Fig. 2

The mammalian expression vectors pMH3-MHCSZ-123VH and pMH3-MHCSZ-123-VK. Both vectors contain GC-rich promoter and chicken beta actin gene intron-1 followed by dhfr cDNA. pMH3-MHC-SZ-123VH contains the variable sequence of the SZ-123 mouse monoclonal antibody heavy chain and constant region sequence of the human IgG1 heavy chain. pMH3-MHC-SZ-123-VK contains the variable sequence of the SZ-123 mouse monoclonal antibody light chain and constant region sequence of the human kappa chain

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