Skip to main content

Table 2 Patient characteristics

From: Incorporation of high-dose 131I-metaiodobenzylguanidine treatment into tandem high-dose chemotherapy and autologous stem cell transplantation for high-risk neuroblastoma: results of the SMC NB-2009 study

Parameters

NB-2004

(n = 50)

NB-2009

(n = 54)

P value

Age (months)

37 (4–129)

30.5 (1–231)

0.460

Age >18 months, n (%)

42 (84.0)

45 (83.3)

0.927

INSS stage, n (%)

  

0.116

 Stage 3

5 (10.0)

2 (3.7)

 

 Stage 4

45 (90.0)

49 (90.7)

 

 Stage 4S

0 (0.0)

3 (5.6)

 

MYCN amplification, n (%)

22 (44.0)

25 (48.1)

0.680

Unfavorable pathology (INPC), n (%)

37/43 (86.0)

39/52 (75.0)

0.180

Serum LDH (IU/L), median (range)

1766 (505–15 720)

1746 (416–14 435)

0.542

Serum ferritin (ng/mL), median (range)

226 (20–3 284)

266 (25–1491)

0.972

Serum NSE (ng/mL), median (range)

141.2 (17.9–1 507.1)

97.6 (10.3–1 815.0)

0.134

24-h urine VMA (mg), median (range)

15.0 (0.7–100.0)

9.3 (0.4–92.4)

0.576

  1. Abbreviations: INSS International Neuroblastoma Staging System, INPC International Neuroblastoma Pathology Classification, LDH lactate dehydrogenase, NSE neuron-specific enolase, VMA vanillylmandelic acid