Table 3 Grade 3/4 toxicities during induction chemotherapy

 Duration of neutropenia, day (range)

6 (0–19)

9 (0–25)

 No. of platelet transfusions, n (range)

2 (0–27)

3 (0–15)

 Neutropenic fever, n (%)

71 (27.2)

94 (44.8)

 Positive blood culture, n (%)

4 (1.5)

12 (5.7)

 Elevation of liver enzymes, n (%)

10 (3.8)

16 (7.6)

 Hyperbilirubinemia, n (%)

1 (0.4)

0 (0.0)

 Renal insufficiency, n (%)

0 (0.0)

0 (0.0)

 Hyponatremia, n (%)

7 (2.9)

4 (1.9)

 Hypokalemia, n (%)

15 (5.7)

13 (6.2)