AE, n (%) | <65 years (n = 97)a | ≥65 to <75 years (n = 98) | ≥75 years (n = 91) |
---|---|---|---|
Patients with ≥1 AE | 91 (93.8) | 95 (96.9) | 89 (97.8) |
Neutropenia | 73 (75.3) | 75 (76.5)† | 57 (62.6) |
Thrombocytopenia | 37 (38.1)‡ | 58 (59.2) | 51 (56.0) |
Anemia | 9 (9.3) | 12 (12.2) | 14 (15.4) |
Leukopenia | 9 (9.3) | 9 (9.2) | 15 (16.5) |
Pneumonia | 4 (4.1) | 10 (10.2) | 9 (9.9) |
Fatigue | 1 (1.0)§ | 8 (8.2) | 3 (3.3) |
Dyspnea | 2 (2.1) | 4 (4.1) | 7 (7.7) |
Febrile neutropenia | 7 (7.2) | 5 (5.1) | 3 (3.3) |
Deep vein thrombosis | 2 (2.1) | 7 (7.1) | 3 (3.3) |
Diarrhea | 6 (6.2) | 7 (7.1) | 5 (5.5) |
Hypokalemia | 4 (4.1) | 1 (1.0) | 6 (6.6) |
Cardiac failure congestive | 0¶ | 2 (2.0) | 5 (5.5) |
Fall | 0¶ | 1 (1.0) | 5 (5.5) |
Alanine aminotransferase increased | 5 (5.2) | 2 (2.0) | 2 (2.2) |
Rash | 4 (4.1) | 5 (5.1) | 4 (4.4) |