Fig. 7

GRIA3 is a direct target of miR-330-3p. a Relative luciferase activity of 293 T cells after co-transfection with wild-type (Wt) or mutant (Mt) GRIA3 3′ UTR reporter genes and miR-330-3p mimics or control. The expression of GRIA3 in H460 and H1975-transfected cells was determined by qRT-PCR (b) and by western blotting (c). d Transwell invasion assays of H460 and H1975 cells transfected with lentivirus either empty (NC-LV) or miR-330-3p (330-3p) followed by GRIA3 or pcDNA control (Vec) vectors. All data were presented as mean of three independent experiments ± SD. *P < 0.05, **P < 0.01, #P < 0.001, one-way ANOVA test