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Table 2 Graft characteristics

From: Single- or double-unit UCBT following RIC in adults with AL: a report from Eurocord, the ALWP and the CTIWP of the EBMT

 

sCBT (n = 172)

dCBT (n = 362)

P value1

Number of HLA disparities, no. (%)

0–1 Mismatch

55 (32)

79 (22)

0.13

2 Mismatches

99 (58)

192 (53)

 

3–4 Mismatches

9 (5)

24 (7)

 

Missing data

9 (5)

67 (18)

 

ABO group, no. (%)

  

0.08

Compatible or minor mismatch

89 (52)

159 (44)

 

Major mismatch

53 (31)

139 (38)

 

Missing data

30 (17)

64 (18)

 

TNC at collection × 107/kg

Median (range)

3.8 (2.5–9.0)

5.1 (1.5–13.7)a

<0.001

CD34+ cell at collection × 105/kg

Median (range)

3.1 (0.6–6.8)

4.0 (0.4–10.4)

0.003

TNC at infusion × 107/kg

Median (range)

3.1 (0.6–6.8)

4 (0.4–10.4)

<0.001

CD34+ cell at infusion × 105/kg

Median (range)

1.2 (0.2–4.9)

1.2 (0.1–8.5)

0.5

  1. a2 Patients had <2.5 × 107 TNC/kg