Fig. 3

Microarray analysis of LIN28B knocking down TF-1a cells. a Relative expression levels for the 108 genes that changed significantly (ANOVA, p < 0.05) and more than 1.4-fold are shown in six columns. Colors indicate relative signal intensities (red: gene upregulation; blue: gene downregulation). The RNA expression profile was sorted using a hierarchical clustering method. A quantitative description of RNA expression levels is presented in Additional file 1: Table S1. Duplication was done and shown in this figure. N/A indicates unknown gene which its sequence might have potential biological effect. b GO analysis revealed that these top five most significant gene cluster variation in LIN28B knocking down TF-1a cells