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Table 1 Summary of ALL samples included in the study

From: Transcriptome sequencing in pediatric acute lymphoblastic leukemia identifies fusion genes associated with distinct DNA methylation profiles

Immuno-phenotype Cytogenetic abnormality Fusion gene N Median WBC at diagnosis, × 10^9/L (range) Median age at diagnosis, years (range)
T-ALL Various   18 173.5 (1–588) 11.9 (1.9–16.8)
BCP-ALL HeH 42 9.6 (0.8–124) 3.6 (1.0–17.74
  t(12;21) ETV6-RUNX1 18 6.5 (1.1–95) 4.9 (2.2–12.7)
  11q23/MLL MLL-r 7 193 (1.8–744) 0.6 (0.5–1.7)
  t(9;22) BCR-ABL1 6 88.3 (14.1–180) 12.1 (9.3–13.5)
  dic(9;20) 1 41.8 (41.8–41.8) 4.4 (4.4–4.4)
  Various (BCP-ALL “other”)a 42 7.9 (0–213) 8.8 (1.4–17.7)
Total    134   
  1. aBCP-ALL samples negative for targeted assays for known ALL cytogenetic aberrations with either non-recurrent aberrations, normal karyotypes, or no results available from cytogenetic analysis
  2. WBC white blood cell count at diagnosis, MLL-r rearrangements involving the KMT2A (MLL) gene