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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: Chimeric antigen receptors for adoptive T cell therapy in acute myeloid leukemia

Fig. 4

Creating a better CAR-expressing T cell. mAb, antibody monoclonal antibody; scFv, single chain antibody fragment; allo-HSCT, allogenic haemopoietic stem cell transplantation; iCasp9, inducible caspase 9; IL12, interleukin-12; LAG3, lymphocyte activating 3; mRNA, messenger ribonucleic acid; PD1, programmed death 1; EGFRt, truncated epidermal growth factor receptor; TRUCKS, T cells redirected for universal cytokine-mediated eliminating antigen-negative cancer cells

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