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Table 2 Outcomes in the 322-patient prospective cohort and correlation with GEP class, SLN status, and ulceration

From: Interim analysis of survival in a prospective, multi-center registry cohort of cutaneous melanoma tested with a prognostic 31-gene expression profile test

 

Recurrence (n* = 25)

Distant metastasis (n = 12)

Death (n = 11)

Class 1 (n = 248)

5 (2%)

2 (1%)

3 (1%)

Class 2 (n = 74)

20 (27%)

10 (14%)

8 (11%)

   p value**

<0.0001

<0.0001

0.0001

SLN− (n = 286)

15 (5%)

6 (2%)

10 (3%)

SLN+ (n = 36)

10 (28%)

6 (17%)

1 (3%)

   p value

<0.0001

<0.001

1

Ulceration absent (n = 264)

10 (4%)

3 (1%)

6 (2%)

Ulceration present (n = 58)

15 (26%)

9 (16%)

5 (9%)

   p value

<0.0001

<0.0001

0.04

  1. *n = number of samples
  2. **p values reflect differences between high and low-risk groups for each prognostic factor (χ 2 test)