Fig. 6

Venn analysis of significantly changed nuclear receptor expression among four different tissues. a, b Venn diagram shows the number of significantly upregulated and downregulated nuclear receptors in four different pathologies respectively (blue, yellow, green and red represent rheumatoid arthritis/ familial hypercholesterolemia/diabetes/obesity). c The nuclear receptor genes that are upregulated, downregulated, and without any expression changes in four pathologies of interest. d The signaling pathways that are regulated by nuclear receptor genes that are upregulated, downregulated, and have no expression changes in four pathologies of interest. e A list of nuclear receptors that can be used as biomarkers to detect indicated pathologies