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Table 1 The UniGene ID of 48 human nuclear receptors and mouse homologs

From: A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors

Gene name (full name) NRNC symbol Receptor Ligand(s) ID
Human Mouse (Mm.)
(Hs.)
Class I—thyroid hormone receptor-like
 THRA Thyroid hormone receptor, alpha NR1A1 Thyroid hormone receptor Thyroid hormone 724 265917
 THRB Thyroid hormone receptor, beta NR1A2 187861 32563
 RARA Etinoic acid receptor, alpha NR1B1 Retinoic acid receptor Vitamin A and related compounds 654583 439744
 RARB Etinoic acid receptor, beta NR1B2 654490 259318
 RARG Etinoic acid receptor, gamma NR1B3 1497 1273
 PPARA Peroxisome proliferator-activated receptor alpha NR1C1 Peroxisome proliferator-activated receptor Fatty acids, prostaglandins 103110 212789
 PPARD Peroxisome proliferator-activated receptor delta NR1C2 696032 328914
 PPARG Peroxisome proliferator-activated receptor gamma NR1C3 162646 3020
 NR1D1 Nuclear receptor subfamily 1 group D member 1 NR1D1 Rev-ErbA Heme 592130 390397
 NR1D2 Nuclear receptor subfamily 1 group D member 2 NR1D2 37288 26587
 RORA RAR-related orphan receptor A NR1F1   Cholesterol 560343 427266
 RORB RAR-related orphan receptor B NR1F2 494178 234641
 RORC RAR-related orphan receptor C NR1F3 256022 4372
 NR1H3 Nuclear receptor subfamily 1 group H member 3 NR1H3 Liver X receptor-like receptor Oxysterols 438863 22690
 NR1H2 Nuclear receptor subfamily 1 group H member 2 NR1H2 432976 968
 NR1H4 Nuclear receptor subfamily 1 group H member 4 NR1H4 282735 3095
 VDR Vitamin D (1,25-dihydroxyvitamin D3) receptor NR1I1 Vitamin D receptor-like receptor Vitamin D 524368 245084
 NR1I2 Nuclear receptor subfamily 1group I member 2 NR1I2 Xenobiotics 7303 8509
 NR1I3 Nuclear receptor subfamily 1 group I member 3 NR1I3 Androstane 349642 486506
Class II—retinoid X receptor-like
 HNF4A Hepatocyte nuclear factor 4, alpha NR2A1 Hepatocyte nuclear factor-4 receptor Fatty acids 116462 202383
 HNF4G Hepatocyte nuclear factor 4, gamma NR2A2 241529 330897
 RXRA Retinoid X receptor alpha NR2B1 Retinoid X receptor Retinoids 590886 24624
 RXRB Retinoid X receptor beta NR2B2 388034 1243
 RXRG Retinoid X receptor gamma NR2B3 26550 3475
 NR2C1 Nuclear receptor subfamily 2 group C member 1 NR2C1 Testicular receptor UD 108301 107483
 NR2C2 Nuclear receptor subfamily 2 group C member 1 NR2C2 555973 87062
 NR2E1 Nuclear receptor subfamily 2 group E member 1 NR2E1 Tailless-like receptors UD 157688 287100
 NR2E3 Nuclear receptor subfamily 2 group E member 3 NR2E3 187354 103641
 NR2F1 Nuclear receptor subfamily 2 group F member 1 NR2F1 COUP-TF-like receptors UD 347991 439653
 NR2F2 Nuclear receptor subfamily 2 group F member 2 NR2F2 519445 158143
 NR2F6 Nuclear receptor subfamily 2 group F member 6 NR2F6 466148 28989
Class III—estrogen receptor-like
 ESR1 Estrogen receptor 1 NR3A1 Estrogen receptor Estrogens 208124 9213
 ESR2 Estrogen receptor 2 NR3A2 660607 2561
 ESRRA Estrogen-related receptor alpha NR3B1 Estrogen-related receptor UD 110849 386776
 ESRRB Estrogen-related receptor beta NR3B2 435845 235550
 ESRRG Estrogen-related receptor gamma NR3B3 444225 89989
 NR3C1 Nuclear receptor subfamily 3 group C member 1 NR3C1 3-Ketosteroid receptors Cortisol 122926 129481
 NR3C2 Nuclear receptor subfamily 3 group C member 2 NR3C2 Aldosterone 163924 324393
 PGR Progesterone receptor NR3C3 Progesterone 32405 12798
 AR Androgen receptor NR3C4 Testosterone 76704 439657
Class IV—nerve growth factor IB-like
 NR4A1 Nuclear receptor subfamily 4 group A member 1 NR4A1 Nerve growth factor IB-like receptors UD 524430 119
 NR4A2 Nuclear receptor subfamily 4 group A member 2 NR4A2 563344 3507
 NR4A3 Nuclear receptor subfamily 4 group A member 3 NR4A3 279522 247261
Class V—steroidogenic factor-like
 NR5A1 Nuclear receptor subfamily 5 group A member 1 NR5A1 Fushi tarazu F1-like receptors Phosphatidylinositols 495108 31387
 NR5A2 Nuclear receptor subfamily 5 group A member 2 NR5A2 33446 16794
Class VI—germ cell nuclear factor-like
 NR6A1 Nuclear receptor subfamily 6 group A member 1 NR6A1 Germ cell nuclear factor receptors UD 586460 439703
Class O—miscellaneous
 NR0B1 Nuclear receptor subfamily 0 group B member 1 NR0B1 DAX-like Receptors UD 268490 5180
 NR0B2 Nuclear receptor subfamily 0 group B member 2 NR0B2 427055 346759
  1. UD undetermined