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Table 10 The Mouse Genome Informatics (MGI) database shows that 26 nuclear receptor deficiencies lead to abnormal metabolism and endocrine and cardiovascular phenotypes in mice

From: A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors

  1. #Disease association of human genes are from the NCBI mim2gene_medgen file and include annotations from OMIM, NCBI curation, Gene. *Abnormal mouse phenotypes. Of note, red fonts indicate cancers, blue fonts indicate autoimmune diseases, and green fonts indicate metabolic disorders such as obesity