Fig. 5
Overexpression of miR-200b prevents EMT and promotes tumor regression. a-b Nude mice (six per group) were subcutaneously injected with 3 × 106 HCCC cells and miR-200b mimics, inhibitor or negative control (10 nM per injection) were delivered via intratumoral injection for six times, 3 days apart. The tumor volume (mm3) and body weight (g) were measured. c-d The level S of AP-2α/MAPK7/TGF-β and EMT markers in tumor tissues was estimated. *p < 0.05, **p < 0.01, ***p < 0.001, data represent the mean ± SD