Table 3 Cox regression analysis of GD2 expression and clinicopathologic factors with overall survival
Factors | Group | HR (95% CI) | P value |
|---|---|---|---|
Univariate analysis | |||
 Age | > 60 vs. ≤ 60 | 1.08 (0.736–1.585) | 0.693 |
 Gender | Male vs. female | 1.005 (0.702–1.438) | 0.98 |
 Ulceration | Yes vs. no | 1.218 (0.841–1.763) | 0.297 |
 Thickness | > 2 vs. ≤ 2 mm | 1.526 (0.843–2.76) | 0.163 |
 TNM stage | I,II vs. III,IV | 2.757 (1.852–4.105) | < 0.0001 |
 Metastasis | Yes vs. no | 2.757 (1.852–4.105) | < 0.0001 |
 GD2 expression | GD2+ vs. GD2− | 1.961 (1.334–2.883) | 0.001 |
Multivariate analysis | |||
 GD2 expression | GD2+ vs. GD2− | 1.547 (1.032–2.317) | 0.035 |
 TNM stage (metastasis) | I,II vs. III, IV (yes vs. no) | 2.405 (1.592–3.633) | < 0.0001 |