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Table 3 Cox regression analysis of GD2 expression and clinicopathologic factors with overall survival

From: Anti-GD2/4-1BB chimeric antigen receptor T cell therapy for the treatment of Chinese melanoma patients

Factors Group HR (95% CI) P value
Univariate analysis
 Age > 60 vs. ≤ 60 1.08 (0.736–1.585) 0.693
 Gender Male vs. female 1.005 (0.702–1.438) 0.98
 Ulceration Yes vs. no 1.218 (0.841–1.763) 0.297
 Thickness > 2 vs. ≤ 2 mm 1.526 (0.843–2.76) 0.163
 TNM stage I,II vs. III,IV 2.757 (1.852–4.105) < 0.0001
 Metastasis Yes vs. no 2.757 (1.852–4.105) < 0.0001
 GD2 expression GD2+ vs. GD2 1.961 (1.334–2.883) 0.001
Multivariate analysis
 GD2 expression GD2+ vs. GD2 1.547 (1.032–2.317) 0.035
 TNM stage (metastasis) I,II vs. III, IV (yes vs. no) 2.405 (1.592–3.633) < 0.0001
  1. CI confidence interval