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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: miR-182-5p promotes hepatocellular carcinoma progression by repressing FOXO3a

Fig. 4

miR-182-5p targets FOXO3a to activate AKT pathway. a Predicted binding sites of 3′-UTR of FOXO3a to miR-182-5p, and the relative Rluc/Luc ratio of dual-luciferase reporter assay in different groups. b Western blot analysis of AKT/FOXO3a signaling-related proteins in control group, overexpression and knockdown miR-182-5p group of HCC cells. c Western blot analysis of p-AKT Ser473 expression after FOXO3a knockdown. d FASC analysis of cell apoptosis rate in miR-NC and miR-182-5p overexpression cells

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