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Table 1 Expression of PD-L1, PD-L2, and PD-1 in musculoskeletal tumors

From: PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse

Tumor

N

PD-L1

N (%)

PD-L2

N (%)

PD-1

N (%)

0

1+

2+

3+

Positive

0

1+

2+

3+

Positive

0

1+

2+

3+

Positive

Musculoskeletal tumor

234

179

35

10

10

55 (23.5%)

168

49

8

9

66 (28.2%)

185

37

5

7

49 (20.9%)

Giant cell tumor

14

4

1

2

7

10 (71.4%)

7

1

1

5

7 (50.0%)

6

1

2

5

8 (57.1%)

Osteosarcoma

62

40

17

3

2

22 (35.5%)

36

21

3

2

26 (41.9%)

45

15

1

1

17 (27.4%)

Synovial sarcoma

127

107

16

3

1

20 (15.7%)

101

22

2

2

26 (20.5%)

103

21

2

1

24 (18.9%)

Chondrosarcoma

31

28

1

2

0

3 (9.7%)

24

5

2

0

7 (22.6%)

31

0

0

0

0

Conventional chondrosarcoma

27

27

0

0

0

0

21

4

2

0

6 (22.2%)

27

0

0

0

0

Dedifferentiated chondrosarcoma

4

1

1

2

0

3 (75.0%)

3

1

0

0

1 (25.0%)

4

0

0

0

0

  1. Abbreviations: PD-L1 programmed death ligand-1, PD-L2 programmed death ligand-2, PD-1 programmed death-1