Fig. 6
From: Artesunate shows potent anti-tumor activity in B-cell lymphoma
Artesunate treatment decreases the metabolic activity of malignant B-cells. a Data pertaining to the oxygen consumption rate (OCR) and b extracellular acidification rate (ECAR), measured in real-time in live intact B-cell lymphoma cells pretreated with artesunate (5 μM, 12 h). A standard “mito-stress assay” as described by the manufacturer was performed on all treatment and cell groups. c Extracted values for basal respiration, ATP-linked respiration, maximal respiration capacity and basal glycolysis. FCCP = carbonyl cyanide-p-trifluoromethoxyphenylhydrazon, anti-A = antimycin A, rot = rotenone. (n = 21)