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Table 2 CBF leukemia constitution in Japanese and Chinese cohorts against European and American cohorts

From: Distinct genetic alteration profiles of acute myeloid leukemia between Caucasian and Eastern Asian population

 

China1a

JALSG AML95, 97, and 201 [13]

China1a

JALSG AML95, 97, and 201 [13]

HOVON/SAKK AML- 42 [7]

ECOG1900 [4]

Median age, years

36

–

46

–

49

48

Age range, years

15–55

15–64

40–55

50–64

17–60

17–60

CBFβ-MYH11, no.

33

107

15

34

44

57

AML1-ETO, no.

131

408

43

134

44

48

CBFβ-MYH11 in CBF (%)

20.1

20.8

25.9

20.2

50.0

54.3

P value (vs. ECOG1900)

< 0.001

< 0.001

< 0.001

< 0.001

0.553

 

P value (vs. HOVON/SAKK AML- 42)

< 0.001

< 0.001

0.004

< 0.001

 

0.553

  1. aData from our cohort (ChiCTR-TRC-10001202)