From: Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel
Vasopressor | Dose for ≥ 3 h |
---|---|
Norepinephrine monotherapy | ≥ 0.20 mcg/kg/min |
Dopamine monotherapy | ≥ 10 mcg/kg/min |
Phenylephrine monotherapy | ≥ 200 mcg/min |
Epinephrine monotherapy | ≥ 0.10 mcg/min |
If on vasopressin | High-dose if vasopressin + norepinephrine equivalent of ≥ 10 mcg/min (using VASST formula)* |
If on combination vasopressors (not vasopressin) | Norepinephrine equivalent of ≥ 20 mcg/min (using VASST formula)* |