A novel generation 1928zT2 CAR T cells induce remission in extramedullary relapse of acute lymphoblastic leukemia

Table 1 The characteristics of enrolled ALL patients with extramedullary involvement

Patient no.	Age (years)	Sex	Recurrent site	Dose*	Response	CRS	allo-HSCT	Outcome^#
No.1	34	F	Breast	0.5	CR on day 46	Grade 2	No	CR
No.2	16	M	BM, kidney	5.0	CR on day 10	Grade 2	Yes	CR
No.3	20	M	CNS, pancreas, pleuroperitoneum, pelvic fascia, and LNs	10	CR on day 18	Grade 3	No	CR

M male, F female, CR complete remission, allo-HSCT allogeneic hematopoietic stem cell transplantation, CRS severe cytokine release syndrome, BM bone marrow, CNS central nervous system; LNs, lymph nodes
*Dose at × 10⁵cells/kg
^#Outcome in October 2017

ISSN: 1756-8722