Fig. 4From: NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cellsNLRX1 induces cell senescence via a P21-dependent pathway. a P21 expression after NLRX1 OE in HCCLM3 cells detected by WB. b Evaluation of the expression levels of two downstream targets of P21, CDK1, and CDK2, after NLRX1 modulation. c Validation of NLRX1 and P21 modulations in HCCLM3 cells by WB assays. d β-galactosidase activity experiments for HCCLM3 cells after different treatmentsBack to article page