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Fig. 7 | Journal of Hematology & Oncology

Fig. 7

From: The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma

Fig. 7

Representative histopathological and immunohistochemical images in T98G tumors treated with TINO and TINO + RT. a, b Hematoxylin/eosin staining for glial appearance of T98G tumors and leukocyte infiltrate. c Different pattern of fibrillar collagen scaffold with necrosis and fibrosis areas evaluated by trichromic stain. d Modification of vascular architecture in TINO and RT + TINO treatments. e Determination of necrotic areas in T98G tumors and comparison amongst experimental groups. f VEGF-A determination on plasma collected from mice bearing T98G tumors and comparison amongst experimental group. g Ki67 staining (proliferating index) in T98G tumors harvested from different experimental group

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Journal of Hematology & Oncology

ISSN: 1756-8722

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