Table 1 Patients and donors characteristics
Haplo | MUD 10/10 | p value | |
|---|---|---|---|
Number | 250 | 2589 | |
Follow-up | 23.18 (1.8–93.9) | 23.02 (0.2–128) | |
Year of Tx | 2013 (2006–2014) | 2012(2001–2014) | < 10− 4 |
Time to Tx (months) | 9 (5.1–18.7) | 6.8 (4.6–15) | 0.001 |
Patient sex | |||
Male | 156 (62%) | 1471 (57%) | 0.093 |
Female | 94 (38%) | 1114 (43%) | |
Missing | 0 | 4 | |
Performance status | |||
KPS ≤ 90 | 97 (41%) | 723 (28%) | 0.001 |
KPS ≥ 90 | 139 (59%) | 1670 (65%) | |
Missing | 14 (0%) | 196 (7%) | |
Age | 65(62.3–66.9) | 64.8(62.2–67.6) | 0.756 |
Disease status | |||
CR1 | 95 (38%) | 1377 (53%) | < 10−4 |
CR ≥ 2 | 46 (18%) | 436 (17%) | |
Active disease | 109 (44%) | 776 (30%) | |
Missing | 0 | 0 | |
Cytogenetics | |||
Good | 17 (10%) | 77 (5%) | 0.036 |
Intermediate | 28 (17%) | 210 (15%) | |
Poor | 31 (18%) | 221 (16%) | |
Secondary AML | 92 (55%) | 902 (64%) | 0.535 |
Missing | 82 | 1179 | |
Previous autologus Tx | 21 (8%) | 49 (2%) | < 10−4 |
Sex mismatch D/R | |||
No F->M | 197 (79%) | 2210 (88%) | < 10− 4 |
F->M | 53 (21%) | 297 (12%) | |
Missing | 0 | 82 | |